Pulmonology and Critical Care Medicine

A novel approach is needed in the therapeutics strategy of dealing with air born disease and respiratory problems.  Lungs are exposed to number of airborne pathogen or toxic as it inhale and exhale more than 10,000 litres of air daily. This airway epithelium responds to such exposure by increasing its production of mediators such as cytokines, chemokines and antimicrobial peptides thus, it triggers or activates body immune system to defence pulmonary circulation of body. Recent findings indicate the importance of these peptides as effector molecules of innate immunity by killing microorganisms, but also as regulators of inflammation, immunity and wound repair.